A break-in and murder at a New York City museum sparks an investigation by Interpol Agent Nathan Nelson. When he finds an ancient artifact, Nelson takes it home to conduct more research. A lightning storm, a pet chameleon and the artifact gives his daughter, Maggie, mystical powers to shape-shift her appearance at will which includes the ability to mimic other people and animals.

Mysterious alien Critters have crash-landed in a small college town, devouring every living thing they encounter. Drea and the kids she's babysitting must try desperately to save themselves from the ravenous, rolling beasts. Will Drea discover her inner badass, and will it be enough to stop the Critter onslaught?

Caught in a bizarre and terrifying time warp, college student Tree finds herself repeatedly reliving the day of her murder, ultimately realizing that she must identify the killer and the reason for her death before her chances of survival run out.