Four losers borrow money from gangsters to bet on a "sure thing", but lose. The gangsters go after them to get their money.

A couple of bumbling 1920s hustlers attempt to obtain the fortune of an heiress. Nothing will stop them, not even murder.

Like most of the people in her town, Karen Silkwood works at the local nuclear plant producing highly radioactive plutonium. Exposed one day to a lethal dose of radiation, Karen faces the blank walls of corporate indifference and denial. As her illness increases, her protest grows louder and she becomes an obvious danger to the powers that be.

She's a magazine writer who gives up her career for love and family. He's a playboy newspaper columnist who can't quite give up his old tricks. And if that combination doesn't give a relationship heartburn, nothing will.

God has abandoned Heaven. It's 1985: the Reagans are in the White House and Death swings the scythe of AIDS. In Manhattan, Prior Walter tells Louis, his lover of four years, he's ill; Louis leaves but asvdisease and loneliness ravage Prior, guilt invades Louis. Joe Pitt, a Mormon Republican attorney, is pushed by right-wing fixer Roy Cohn toward a job at the Justice Department. Pitt and Cohn are closeted: Pitt, out of shame and religious turmoil; Cohn, to preserve his power and access. Pitt's wife Harper is strung out on Valium, aching to escape a sexless marriage. An angel invites Prior to be a prophet in death.