In a world where humans and demons are sworn enemies, humanity's greatest hero forms an unlikely alliance with the Demon Queen in hopes of ending war.

A talented young witch embarks on a journey without end, finding new adventures in different places before she flies off to her next destination.

After meeting one day, a shy boy who expresses himself through haiku and a bubbly but self-conscious girl share a brief, magical summer.

Yuta Okkotsu is a nervous high school student who is suffering from a serious problem—his childhood friend Rika has turned into a curse and won't leave him alone. Since Rika is no ordinary curse, his plight is noticed by Satoru Gojo, a teacher at Jujutsu High, a school where fledgling exorcists learn how to combat curses. Gojo convinces Yuta to enroll, but can he learn enough in time to confront the curse that haunts him?

中世纪，炼金术士们以巨大的代价从恶魔的手中得到了传说中的永生之酒，凡是喝下永生之酒的人们，正如它的名字那样，将会得到永远不会死亡的肉体。永生之酒带来了希望，却也引发了空前绝后的灾难，因为私欲和利益，与此酒相关的人士一个接着一个失去了踪迹。随着禁酒令的颁布，永生之酒的下落逐渐成为了谜题，然而数年过后，有关它重出江湖的消息再次被传得沸沸扬扬，在纽约的黑道中激起了涟漪。
身怀绝技的少年洛菲（吉野裕行 配音）、不老不死的炼金术士阿洛瓦（宫本充 配音）、个性莽撞大大咧咧的夫妻艾萨克（小野坂昌也 配音）和哈文特（青木静香 配音），这些身份从无交集的人们，也为了追寻永生之酒的下落而走到了一起。