阳光帅气的齐藤英二郎（妻夫木聪 饰）结束了名门学府永禄大学医学系的学业，和同期出久根邦弥（加藤浩次 饰）以精英的身份留在永大医院实习。但现实与理想有着巨大的差距，他每天工作超过16个小时，报酬却低的可怜。为此英二郎工作之余跑到另一家医院兼职。见惯了医疗界丑恶一面，齐藤却无法做出彻底的改变，更错过了好不容易得到的手术机会，由此导致护士赤城香织（铃木京香 饰）离职。几经周折，齐藤总算重新打起精神，他周转于内科、NICU、急诊室，在顶住各种不正常现象所带来的压力的同时，全心全意奔走在救助病患的道路上，只为践行一名医者的良心……
本片根据佐藤秀峰的漫画改编。

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