A bizarre black comedy about a man whose overwhelming ambition in life is to be a renowned serial killer of women, and will stop at nothing to achieve it - but not everything goes according to plan...

In 1965 Mexico City, Flavia, a wealthy yet lonely schoolgirl, befriends Veronica, a young orphan girl who has a fascination with witchcraft. Veronica convinces Flavia that she is a real witch and forces her to be her assistant. The children's games gradually become more serious and Veronica demands more from Flavia.

A terrible disease is found in a Mexican town. A doctor tries to alert the authorities when he discovers its epidemic nature. No one listen to him and soon after the disease spreads. The government tries to control the information in order to prevent panic.

Five surreal short stories make up this Mexican anthology film.

When a worker is found murdered on the construction side, the investigation swiftly turns from things criminal to the political circumstances surrounding the building itself. Widespread corruption and neglect by the builder himself are seen to have brought the situation about. Much of the movie is filmed using hand-held cameras, and the majority of the dialogue is in the difficult-to-understand and very slangy Spanish dialect of Mexico City's bricklayers.