She Wolf is a serial killer who traps her men in the subway in Buenos Aires. She seduces, has sex with them and kills them. But one of those men is a police officer who is investigating her crimes. Running away from him she meets a dealer with whom she stars a relationship. This romance unravels a war between her three personalities: the monster woman, the sensual woman and the human woman who can still love.

Four characters are looking for a man called Castro, but we don't know why. For some mysterious reason, Castro is running. He has left his life behind, and survives by hiding in a room in a small city. He is basically alone, but someone has appeared in his life, Celia. She is young, beautiful, and sometimes cruel.