Physician Carole Nelson, suspected of having ties to notorious gangster Joe Gurney, must prove her innocence or the Medical Board will revoke her license. When Gurney seeks her out for treatment after being shot, it could be the break Nelson needs. Now she has a chance to use her medical know-how to outwit Gurney and his goons and reestablish her professional reputation.

Reporter Jane Arden goes undercover to try to expose a gang of jewel thieves and smugglers. Her mission becomes more dangerous when her identity is discovered early on by one of the gang leaders.

In the slums, teenager Frankie Warren hangs out with a rowdy gang who one day knock him out in a fight. In court, the boys refuse to reveal who struck the knockout blow, and all are subsequently sentenced to a reformatory, cruelly run by two corrupt guards. New deputy commissioner Mark Braden arrives determined to change things, but despite the help of Frankie's sister, Mark's reform plans -- and Frankie's future -- may be sabotaged from within.