A theatrical star, born on the wrong side of the tracks, marries a drunken blue-blood millionaire.

In London, barrister Anthony Keane takes the case of Maddalena Paradine, a beautiful woman accused of poisoning her blind husband. Though happily married, Keane becomes infatuated with his enigmatic client and convinced of her innocence. His obsession clouds his judgment as he builds a defense implicating her servant, André Latour—an act that leads to devastating consequences both in court and at home.

Beautiful half-breed Pearl Chavez becomes the ward of her dead father's first love and finds herself torn between her sons, one good and the other bad.