Shortly before her wedding, art gallery director Nora travels from Paris to Grenoble to visit her preteen son, Elias, who is spending time with her aging professor father, Louis, recently diagnosed with terminal cancer. During her stay, she reaches out to her former lover, Ismaël, a viola player and father figure to Elias who has been committed against his will to a mental hospital. Ismaël, however, has his own problems to sort out.

When their regal matriarch falls ill, the troubled Vuillard family come together for a hesitant Christmastime reunion. Among them is rebellious ne'er-do-well Henri and the uptight Elizabeth. Together under the same roof for the first time in many years, their intricate, long denied resentments and yearnings emerge again.

Just as the disheveled and alcoholic filmmaker Ismaël embarks on a difficult new film project, his life is sent into a tailspin. His wife Carlotta, presumed dead for 20 years, come crashing back into his life creating chaos in his work and his current romantic relationship with the starry-eyed astronomer Sylvia.

An American writer living in exile in London, Philip listens to women. His English mistress, who visits him regularly in the studio that serves as their refuge. A student he loved in another life. A former lover confined to a hospital in New York.

Returning to France after a long exile, pianist Mathias Vogler reunites with his mentor, Elena, to prepare a concert. In a park, an encounter with a child who looks just like him will lead him to Claude, the woman he once loved.

Paul is preparing to leave Tajikistan, while thinking back on his adolescent years. His childhood, his mother's madness, the parties, the trip to the USSR where he lost his virginity, the friend who betrayed him and the love of his life.