David and Cassie Osborne have an argument one night. So the next morning after David goes to work, Cassie runs off to her sister's house for a few days with their daughter Samantha. Only they never get there. David starts looking for them, and her sister, Joanne, thinks David had something to do with their disappearance, and calls the police. Actually Samantha and Cassie are with Roy and Georgina Scudder, and their daughter Jill. Roy picked them up after their car broke down. The only problem is, the Scudders, who seem a little odd at first, won't let them leave or call anyone.

A hardened New Orleans cop, Dave Robicheaux, finally tosses in the badge and settles into life on the bayou with his wife. But a bizarre plane crash draws him back into the fray when his family is viciously threatened.

The early years of a television sports powerhouse are chronicled as ABC becomes a player in the NFL coverage by putting their full resources into a major showcase. Executive Roone Arledge recruits former Dallas Cowboys quarterback 'Dandy' Don Meredith, Keith Jackson, and the combative Howard Cosell as commentators for the broadcasts, which become funny, odd trio events to millions of viewers. Jackson departs the show after the first year to take over the network's focus on college football, and former New York Giants star Frank Gifford takes his place, ruffling Cosell's feathers. Then things get really crazy!