The two Warner Brothers Yakko and Wakko and their Warner sister Dot had been (supposedly) created in the 1930's, but their cartoons were too screwy for the general public to handle. The three Warners were locked up in the studio water tower until they escaped in the 90's. There, they run wild, causing chaos everywhere!

After a small earthquake in a tiny, quiet town, local citizens start to exhibit bizarre, violent and self-destructive behaviour.

The Warner Brothers (and the Warner Sister) go on a quest to find a fallen wishing star to help Dot with her illness. Unfortunately the rest of the town, including an evil king, also hear about the star and want to get to it first to have their own wishes come true. It's a race against time and it's up to the three zany siblings to get there first.

Jenny is sent to a women's reform school. It is run by evil warden Sutter and her henchwoman Edna. Jenny will stop at nothing to escape but she also has to deal with Charlie the bully.