A terminally ill girl named Himari Takakura is miraculously saved from death by a strange spirit who resides in a penguin-shaped hat. However, in exchange for extending her life, the spirit tasks Himari's brothers, Kanba and Shōma, to seek out an elusive item known as the Penguin Drum with assistance from a trio of strange penguins.

High school student Chiyo Sakura has a crush on schoolmate Umetarō Nozaki, but when she confesses her love to him, he mistakes her for a fan and gives her an autograph. When she says that she always wants to be with him, he invites her to his house and has her help on some drawings. Chiyo discovers that Nozaki is actually a renowned shōjo manga artist named Sakiko Yumeno. She then agrees to be his assistant in order to get closer to him. As they work on his manga Let's Fall in Love (恋しよっ), they encounter other schoolmates who assist them or serve as inspirations for characters in the stories.

Yuugo Hachiken enrolled in Ooezo Agricultural High School for the reason that he could live in a dorm there. In some ways he chose Ooezo in an effort to escape the highly competitive prep schools he had attended previously, but he was faced with an entirely new set of difficulties at Oezo, surrounded by animals and Mother Nature. After growing up in an average family, he began to encounter clubs and training the likes of which he had never seen before.

High schooler Wakana Gojo wants to become a kashirashi—a master craftsman who makes traditional Japanese Hina dolls. Though he's gung-ho about the craft, he knows nothing about the latest trends, and has a hard time fitting in with his class. The popular kids—especially one girl, Marin Kitagawa—seem like they live in a completely different world. That all changes one day, when she shares an unexpected secret with him, and their completely different worlds collide.

Kenichi Yamada, a single, 35-year-old businessman, has spent the majority of his adult life playing every MMORPG to hit the market. Tired of the constant cycle of repetitive, newbie-centric gameplay, he is immediately drawn in by the promise of a new game that, on top of being never-ending, offers up a "Hell Mode"—a difficulty level that makes it nigh impossible to level up but also promises uncapped growth potential. Upon selecting the newly released Summoner class, Kenichi finds himself reborn as Allen, an infant in a serf family, with nothing but his wits and old memories to guide him.

The story centers around Yoshizou Yukawa, a major hot spring fan who finds hidden springs to revitalize the economy of the local area. However, he dies after falling off a cliff and is transported to an alternate world, thanks to an inari deity of harvest at a small shrine nestled in the rocks. Together with the inari's attendant princess Mayudama, he continues searching for storied hot springs, only this time in the alternate world. Along the way, he ends up naked in hot springs with furry-eared girls and elven girls.