The story revolves around Ogino, who is in the last year of his medical studies. Between lectures, exams, on field training, his commitment as a pro-reformist militant and his girlfriend, Ogino is starting to wonder if he's really cut out to be a doctor.

The story of beautiful Christian nun, Kyoko who is the object of affection for two very different men - one the happy-go-lucky yakuza gangster, Haruhiko who is the next-in-line to takeover the ragtag "Tenryu Gumi" gang and the other bumbling police detective Kumashiro. The Tenryu Gumi is a collection of misfits and other troublemakers but are relatively peaceful due to their Christian beliefs. Their bitter rivals are the more traditional "Kuroiwa Gumi", a much more sadistic and violent group led by godfather Kuroiwa.

Professor Sarusawa and his psychic daughter Mai live together after the suicide of the Professor's wife years earlier - which was caused by a suicide plague running rampant throughout the city. Dr. Aryo lives in a nearby castle with his wife, whom Dr. Aryo created, and a hunchbacked assistant. Dr. Aryo once worked at the same university with Professor Sarusawa but was fired for his morbid experiments. Now, Dr. Aryo may hold the key to unlocking the origins & cure for the suicide virus which Professor Sarusawa may now have. Meanwhile Professor Sarusawa's daughter Mai can be bring to life Dr. Aryo's stitched up cadavers which Dr. Aryo hopes to create a new race with.