The Coast Guard makes a daring rescue attempt off the coast of Cape Cod after a pair of oil tankers are destroyed during a blizzard in 1952.

Escaping from poverty to become a witcher, Vesemir slays monsters for coin and glory, but when a new menace rises, he must face the demons of his past.

In Season 2, after Jesse accidentally discovered that God is absent from Heaven, the three of them set out on a road trip to find Him, all while being hunted by the Saint of Killers, an unstoppable, mythical killer from Hell. The trio’s pursuit led them to New Orleans, where they dodged local gangsters, dangerous agents, and other unimaginable mayhem on their way to uncovering an even bigger secret. Now, with Tulip’s life and Cassidy’s friendship in the balance, Jesse must rely on a mysterious figure from his past in order to save his friends and continue on with his mission.

After witnessing her parents’ murder as a child in Bogota, Cataleya Restrepo grows up to be a stone-cold assassin. She works for her uncle as a hitman by day, but her personal time is spent engaging in vigilante murders that she hopes will lead her to her ultimate target: the mobster responsible for her parents' death.

Fulfilling a promise to his deceased father, one-time outlaw Jesse Custer returns home to West Texas to take over his dad's church. Jesse's mission, however, becomes twisted when his body is overcome by a cryptic force that unleashes within him a highly unconventional power. Together with hell-raising ex-girlfriend Tulip and Irish vagabond Cassidy, the preacher-in-training embarks on a journey to find God in a world inhabited by holy, hellish, and everything-in-between characters.