The third episode of the Cities of Love franchise, Rio, I Love You is an anthology, created by 10 visionary directors from across the globe. The story line of each segment focuses on an encounter of love in a different neighborhood of the city, demonstrating the distinctive qualities and character of that location. The film serves to bridge gaps between cultures, educating and entertaining the audience, while celebrating unique and universal expressions of love.

A disparate group of characters unknowingly bond by the sexual choices they make. Consumed by loneliness, a British businessman ponders a rendezvous with a prostitute. The businessman's wife prepares to call it quits with her younger lover. A Brazilian student breaks up with her boyfriend in London. A recovering alcoholic travels to Phoenix in search of his missing daughter. A paroled sex offender struggles to stay composed when propositioned in a Denver airport. A widower's religious devotion is put to a difficult test.

Frustrated with the direction of the church, Cardinal Bergoglio requests permission to retire in 2012 from Pope Benedict. Instead, facing scandal and self-doubt, the introspective Pope Benedict summons his harshest critic and future successor to Rome to reveal a secret that would shake the foundations of the Catholic Church.

Justin Quayle is a low-level British diplomat who has always gone about his work very quietly, not causing any problems. But after his radical wife Tessa is killed he becomes determined to find out why, thrusting himself into the middle of a very dangerous conspiracy.

When a sudden plague of blindness devastates a city, a small group of the afflicted band together to triumphantly overcome the horrific conditions of their imposed quarantine.

John Sugar is a dashing private eye navigating the dark corners of sunny LA. Though he sees only the good in humanity, Sugar is haunted by a secret too dangerous to expose.

In the poverty-stricken favelas of Rio de Janeiro in the 1970s, two young men choose different paths. Rocket is a budding photographer who documents the increasing drug-related violence of his neighborhood, while José “Zé” Pequeno is an ambitious drug dealer diving into a dangerous life of crime.