Season 5 is the first to move past the original SKAM storylines, centering around Elia Santini. He struggles with toxic masculinity and sexual intimacy, as well as being forced to repeat his senior year of high school without his friends. Throughout the season, he finds himself drawn to classmate Viola.

Season 4 focused on Sana Allagui, a Muslim-Italian girl. She begins to struggle to balance her faith and her friendships, as she begins to develop feelings for her brother's best friend, Malik.

Season 3 focused on Eleonora Sava. She lives with her older brother, completely independent from their parents, and prides herself on being wise beyond her years. However, her confidence threatens to come crashing down when she has to face her romantic feelings for Edoardo, a popular boy at school.

Season 2 broke from the traditional SKAM order of central characters by centering on Martino Rametta, a closeted gay teenager who quickly finds himself falling in love with Niccolò. Leaning on his friends Giovanni, Luca, and Elia, Martino begins to embrace who he truly is

The first season centered around Eva Brighi, a teenage girl who struggles to trust her boyfriend, Giovanni. Eva eventually finds new friends in Eleonora, Federica, Sana, and Silvia, and focuses on herself for a change.

Nic, also called "Lovely Boy", is the rising star of the roman suburbs. Tattoos and pure talent, he creates the XXG with his friend Borneo, a music duo that is headed straight to the top. Nic is then sucked into a spiral of self-destruction, which will lead him to a breaking point: he will soon have to deal with himself.

Christian is an extremely talented as well as unpredictable football player. After his latest screw-up, the president of his team decides to assign him a personal tutor, to help him in controlling his temper. Valerio is a shy and solitary professor, the exact opposite of the champion. Sparks will fly between the two at first, but soon their relationship will change both for the better.

An italian version of the acclaimed and mingtian6.com innovative Norwegian youth series Skam, which follows a group of teenagers in their everyday life of school, love and leisure time.