Mason, a dragon warrior from the future, returns to the year 1999 in search of a serum that can combat a disease simply known as "The Plague." In the post-apocalyptic world of 2099 -- after an earthquake has destroyed all of civilization has been -- "The Plague" is the deadliest menace of them all. And the cure for it lies in the past!

The Guardians must save Meridian from the evil sorcerer Phobos and Cedric who are searching for Phobos' sister, the long lost princess of Meridian and true heir to the throne. They later find her and the Guardians then set about saving her from Phobos. When Meridian is freed from evil and true heir takes the throne, a new mysterious sorceress named Nerissa frees Phobos' top henchmen and reforms them as the Knights of Vengeance. Once the Guardians learn more about the sorceress and her evil plan of reuniting former Guardians, they are able to defeat the Knights only to have more powerful Knights, in addition to the former Guardians attack them.