Dallas housewife Lurene Hallett's life revolves around the doings of Jacqueline Kennedy. She is devastated when President Kennedy is shot a few hours after she sees him arrive in Dallas. Despite her husband Ray's prohibition, she decides to attend the funeral in Washington, D.C. Forced to travel by bus, she befriends Jonell, the young black daughter of Paul Couter. Sensing something wrong, her good intentioned interference leads the mixed race threesome on an increasingly difficult journey to Washington with both the police and Ray looking for them.

The daughter of a former Hooter's waitress and an ex-pro wrestler, Margo is a recent college dropout and aspiring writer. Faced with a new baby, mounting pile of bills, and dwindling number of ways to pay them, Margo must find a way forward.

The lives of an Iowa farmer's three daughters are shattered when he suddenly decides to bequeath them the family's fertile farm.

Melanie Parker, an architect and mother of Sammy, and Jack Taylor, a newspaper columnist and father of Maggie, are both divorced. They meet one morning when overwhelmed Jack is left unexpectedly with Maggie and forgets that Melanie was to take her to school. As a result, both children miss their school field trip and are stuck with the parents. The two adults project their negative stereotypes of ex-spouses on each other, but end up needing to rely on each other to watch the children as each must save his job. Humor is added by Sammy's propensity for lodging objects in his nose and Maggie's tendency to wander.