Shimazu Toyohisa is a real-life samurai who fought in the pivotal Battle of Sekigahara. In his dying moments, Shimazu is transported to a world of magic with other famous warriors throughout history. These warriors are forced to fight each other in an endless battle.

A large scale catastrophe is occurring across the planet. Ability users are discovered after the appearance of a mysterious fog, apparently having committed suicide, so the Armed Detective Agency sets out to investigate these mysterious deaths. The case seems to involve an unknown ability user referred to as "Collector," a man who could be the mastermind behind the incident.
Trust and courage are put to the test in order to save the city of Yokohama and ability users across the world from the grip of Collector where the Armed Detective Agency forms an unlikely partnership with the dangerous Port Mafia.

Five years after the death of the Emperor of Marmo in the War of Heroes, Parn is now the Free Knight of Lodoss, he and his old allies now famous through the land. However, the Emperor's right-hand-man, Ashram, seeks the Scepter of Domination to re-unify Lodoss under his former leader's banner. Meanwhile, beyond his attempts at conquest lies a more sinister force beginning to set the stage for the resurrection of the goddess of death and destruction...

Forty years ago, the minds of Paradigm City's inhabitants were wiped clean of all recollections of the past. Now, ruled by a powerful corporation and cut off from the rest of the world by desolate wastelands, Paradigm has become a virtual police state where Negotiators like Roger Smith keep the wheels of progress, commerce, and society turning.

Forty years ago, the minds of Paradigm City's inhabitants were wiped clean of all recollections of the past. Now, ruled by a powerful corporation and cut off from the rest of the world by desolate wastelands, Paradigm has become a virtual police state where Negotiators like Roger Smith keep the wheels of progress, commerce, and society turning.

On the night of his 30th birthday, one man’s dreams of wielding magic come true after he unexpectedly passes away. He wakes as Sion, a young child in another world. He and his elder sister, Marie, are the children of a lower-class noble family who govern their region. After receiving conflicting messages from their father, Sion and Marie set out on an adventure to uncover the magic.

A story set in the mid-1800's about a young doctor who has been trained in Western-style medicine and a young samurai who is trying to live up to the old traditions of his class and culture. The story is actually based upon real people - the doctor, Ryo-an, was Tezuka's great grandfather.

The manga series was adapted to anime by Madhouse Studios and premiered in Japan on NTV on April 4, 2000.

During the Second Year of Ansei (1855) in Edo's Koishigawa are two young men, Manjiro Ibutani and Ryoan Tezuka. Ibutani is a low-ranking samurai who is a gifted swordsman and has a straightforward and strong sense of justice. Tezuka has a more carefree attitude. He has an eye for the ladies, but he is passionate about becoming a doctor. The two opposite characters come of age during the backdrop of the turbulent end of the Tokugawa Period (1600-1868 CE).