A DNA experiment on a rare breed of spider is taking place on a NASA space shuttle, when a freak meteor shower engulfs the shuttle, causing everything to go horribly wrong. One survivor is found on the ship and watched over in a secret location deep in the California desert. The problem continues, as the survivor isn't alone, as another deadly spiders climbs out of him and goes on a rampage around the ship. Curious reporter Marci Eyre must now survive, escape and warn everyone before the spider reaches outside the desert.

David Cuevas is a family man who works as a gangland tax collector for high ranking Los Angeles gang members. He makes collections across the city with his partner Creeper making sure people pay up or will see retaliation. An old threat returns to Los Angeles that puts everything David loves in harm’s way.