Dr. Elson Po is one of the world's most famous wine growers and has a magic potion which has kept him handsome and alive for centuries. However, the magic which rejuvenates him seems to become less and less effective. As a side project, he makes movies and invites a group of young, aspiring actors to his island for a party, believing that the young, beautiful actress, Jezebel, can be his new source of life.

The arrival of an amnesiac patient in a psychiatric hospital somehow frees a mad doctor, who was shot and entombed with his fiendish experiments in an abandoned wing of the asylum 20 years before.