A private detective, who has been shot, stumbles into the office of Michael Shayne (Hugh Beaumont), and dies before Shayne can question him. Shayne finds a baggage ticket in his hand. He claims it and finds the checked-bag contains the loot from a robbery. Now, he has about fifty minutes left of the running time to find the crooks, bring them to justice and return the money to the rightful owners. And needs all of it.

In the second of the PRC "Michael Shayne" series,civic crusader Burton Stallings hires private detective Michael Shayne to locate the former's missing step-daughter Helen. Shayne discovers that Stallings himself has had Helen confined in an asylum in order to obtain her money.

Michael Shayne is a private detective who is disliked greatly by Pete Rafferty, local chief of police detectives. Rafferty notifies the newspaper press that he is going to close Shayne's agency, just as Michael is about to be hired by the wealthy Eleanor Ramsey, who is being blackmailed. She is the stepmother of what she considers to be two grown-up brats, Dorothy and Ernest, and she considers their father to be of little value to the world himself. They all conspire to get their hands on her money, even to the extent of attempting to hire Shayne to frame an insurance robbery. Mrs. Ramsey is murdered, and Rafferty is trying to pin the killing on Shayne, despite the fact that suspicion points to Buell Renslow, brother of the slain woman. Shayne's secretary, the fetching Phyllis Hamilton, decides to do a little detective work to help her boss.

Hoping to put the cuffs on criminal mastermind Socks Barstow, detective Mike Hanrohan is stymied by the fact that his younger brother Denny has joined Barstow's gang. Things get worse after a bloody shootout, in which Mike apparently guns down his own brother.

A soldier survives a bombing in which his three fellow soldiers were killed. When he recovers he discovers he has amnesia, and since his companions' bodies were burned beyond recognition, the army doesn't know which one of the four he is. He goes AWOL and searches out the families of the three dead soldiers, hoping to find out his own identity.