The Ganso and Honke are two medical wholesalers which have had a long history of exchanges. They were originally a wholesaler set up by Tokiya Manemon who invented a drug. After he fell ill, he imparted the formula to his two beloved disciples. But the two were at loggerheads and the enmity between them caused a split into two factions, the ‘original’ (Ganso) and the ‘originator’ (Honke). One day, an incident finally occurred. Kiichiro (Endo Kaname), the eldest son of the Honke, launched an attack on the young master of the Ganso, Nagahiko (Oshinari Shugo).

Genji and his victorious G.P.S. alliance find themselves facing down a new challenge by the students of Hosen Academy, feared by everyone as 'The Army of Killers.' The two schools, in fact, have a history of bad blood between them. And the simmering embers of hatred are about to flare up again, burning away any last remnants of the truce they had so rigorously observed until now.