One hot summer day a little girl gets lost in an enchanted forest of the mountain god where spirits reside. A young boy appears before her, but she cannot touch him for fear of making him disappear. And so a wondrous adventure awaits...

Set directly after the events of Made in Abyss: Dawn of the Deep Soul, the fifth installment of Made in Abyss covers the adventure of Reg, Riko and Nanachi in the Sixth Layer, The Capital of the Unreturned.

On August 16, midway through a seemingly endless summer vacation, middle school third-year student Nagara, the mysterious transfer student Nozomi, and classmates such as Mizuho and Asakaze, are suddenly transported from their tranquil daily lives to a school adrift in an alternate dimension. They must survive with the super powers that have awakened within them.

A continuation of the epic adventure of plucky Riko and Reg who are joined by their new friend Nanachi. Together they descend into the Abyss' treacherous fifth layer, the Sea of Corpses, and encounter the mysterious Bondrewd, a legendary White Whistle whose shadow looms over Nanachi's troubled past. Bondrewd is ingratiatingly hospitable, but the brave adventurers know things are not always as they seem in the enigmatic Abyss.

While under the guise of taking his family on a weekend winter getaway, Loid's attempt to make progress on his current mission Operation Strix proves difficult when Anya mistakenly gets involved and triggers events that threaten world peace.

Hōzuki is the aide to the great king of Hell, King Enma. Calm and super-sadistic, Hōzuki tries to resolve the various problems in Hell, including a rampaging Momotarō and his companions. However, he also likes spending his free time on his hobbies, such as fawning over cute animals and raising "Goldfish Flowers."

When a ghost-infecting virus known as Fire-Starter begins spreading through the system resulting in the assassination of the Japanese Prime Minister, Major Motoko Kusanagi and her elite team of special operatives are called in to track down its source.

What would have happened if the Shiroyasha never existed? Edo is thrown to chaos by a mysterious cause. Sakata Gintoki, now lives in a world where the future has changed, without him. What has happened to the Yorozuya? Gintoki, who is now a ghost of the past, must once again carry the burden in order to save his friends. He must finish the biggest job ever, which may be the final job of Yorozuya.

Once upon a time, in a far, faraway place, there were two lands. The world was divided into an inner land and an outer land. People feared the outer land, inhabited by eerie beings, the carriers of curse. One day, on the border to the inner land inhabited by humans, one such being finds a girl on heaps of abandoned dead bodies. The girl says her name is Shiva and shows affection to the "being" who found her, calling him "Teacher." This is a story of two people—one human, one inhuman—who linger in the hazy twilight that separates night from day.

The students of Class 3-E have a mission: kill their teacher before graduation. He has already destroyed the moon, and has promised to destroy the Earth if he can not be killed within a year. But how can this class of misfits kill a tentacled monster, capable of reaching Mach 20 speed, who may be the best teacher any of them have ever had?