Paul Hanganu loves two women. Adriana his wife and the mother of their daughter, the woman with whom he's shared the thrills of the past ten years, and Raluca the woman who has made him redefine himself. He has to leave one of them before Christmas.

After suffering terrible headaches and stomach cramps, Mr. Lăzărescu, a lonely 63 year-old man, calls for an ambulance, beginning one man’s hellish journey through Bucharest hospitals in search of proper medical care. As the night unfolds, his health starts to deteriorate fast.