Playboy Larry Blendon introduces his grandmother Stella Blendon to his fiancée, radio singer Virginia Berneaux. Despite Larry's record of broken romances and divorces, Virginia decides she will marry him. Virginia is slain that night and Blandon telephones his friend, Philo Vance, to help find the killer.

Private Detective Philo Vance gets involved with a succession of murders and a mystery concerning the disappearance of an emerald that has been smuggled into the United States.

Framed for two crimes he didn't commit, and betrayed by his girl, Cliff Banks finds himself on the run from the police. Now distrustful of everyone, he finds a safe haven hiding out at a quaint country cottage under the care of a kindly old farmer and his daughter, a Cinderella-like blind woman who seems to be able to communicate with nature. There he is forced by their love to question his misanthropy.