Six months after the D-Reaper was destroyed, the Tamers are planning to throw Rika a surprise party, but Rika finds out. Suddenly a train-Digimon named Locomon begins to race around the tracks, causing havoc. The Tamers respond to this, as Takato digivolves Guilmon into Growlmon to stop the train Digimon but fails as Takato, Rika and Renamon get on it in an attempt to slow it down. The others, excluding Suzie, use a freight train to catch up with Locomon

Tsubomi Hanasaki is a girl in the second grade of middle school who likes flowers and plants. One day she experiences a weird dream. In that dream, a large blooming tree appears. Suddenly, it loses all of its flowers and 2 fairies appear. A few days later after Tsubomi has transferred to Myoudou Academy, suddenly the fairies from the dream appear before her and plead to Tsubomi to become the legendary warrior Pretty Cure, and protect the Heart Tree. However, Tsubomi declines as she doesn't think that she would be able to do that. However, a mysterious enemy suddenly strikes and steals the Heart Flower of her classmate, Erika Kurumi. Now she doesn't have a choice. To retrieve Erika's Heart Flower, she has to transform into a Pretty Cure and fight. Working up the courage, Tsubomi turns into Cure Blossom and a new chapter of Pretty Cure begins!

Takato, Ruki, and Lee are children who have, by fate, received real Digimon, unlike the imaginary ones in the card game they play. Each of the children, or Digimon Tamers, have their different views on how Digimon should be treated. But when other Digimon begin to appear around Japan, they must put aside their differences to fend off the digital intruders.

Omnimon confronts Mephistomon (who was formed from Apocalymon's data) in a dark corner of the Digital World over Mephistomon's attempt to destroy both the Digital World and the Real World and incorporate the data in order to become truly invincible. They fight, but then Mephistomon sees a chance and slips into the Real World.

Only legendary Japanese garage rock band Guitar Wolf can stand between a race of aliens from destroying earth with an army of zombies.

Lain—driven by the abrupt suicide of a classmate—logs on to the Wired and promptly loses herself in a twisted mass of hallucinations, memories, and interconnected-psyches.