Nikita is a drug-addicted juvenile delinquent who was accused of killing a police officer in cold blood during an attempted robbery of a pharmacy. She is later arrested and sentenced to death by lethal injection, upon which she was secretly drugged by the government, faking her death. Nikita is then "recruited" by a secret government organization and transformed into a highly skilled assassin who cannot be traced.

It is 1957. J.C. Cullen is a young man from a small town, with a talent for winning at craps, who leaves for the big city to work as a professional gambler. While there, he breaks the bank at a private craps game at the Gem Club, owned by George Cole, and falls in love with two women, one of them Cole's wife.

An ex-junkie takes on seedy urban culture to try and locate his daughter.