Coslada, near Madrid, Spain, October 2015. Hundreds of extras are trapped in a huge stage where they pretend with hysterical joy that they are celebrating a party that will be broadcast on television on New Year's Eve. But more than a week later, the clash between several staff members threatens to prolong indefinitely such a maddening nightmare.

She's sexy, shameless and loves taking people to their limit. She's a dangerous young woman who dreams about a jaguar that licks her naked body and sleeps by her side. Her past is bathed in blood and weird passions. Now she's met the man of her wildest dreams. He's dark, tough and mysterious. He likes robbing banks, trafficking in corpses and spicing it all with voodoo rituals. Together, the duo sets off toward Mexico destined to become the most feared outlaws in the continent.

The story revolves around a Basque Roman Catholic priest dedicated to committing as many sins as possible, a death metal salesman from Carabanchel, and the Italian host of a TV show on the occult. These go on a literal "trip" through Christmas-time Madrid to hunt for and prevent the reincarnation of the Antichrist.