Within days after the mysterious new student Kawakami Tomie joins a high school classroom, all hell literally breaks loose. Simple in-fighting between boys and girls over Tomie's oppressive shadow soon gives way to mind-breaking violence, culminating in a grizzly dissection that ultimately leads to suicide, insanity, and even more violence.

Following some trauma in her past that has since been repressed, a young woman is trying to recover her memories with the help of a psychiatrist. During her hypnosis sessions, she repeats the name "Tomie" but is unable to recall where she knows it from. Meanwhile, a police detective is investigating a string of brutal murders, where he also runs across the name "Tomie." How are the two connected?

Kou created songs and uploads them to the Internet, and Yuka and Saki enjoy his music as fans, always listening with deep interest and admiration. Their final summer vacation has begun as junior high school students.