The goings on of a few members of a radio show's audience is the premise for this feature film derived from the popular ABC radio show of the 1940s. This film features Tom Breneman, the radio show's host, as well as Bonita Granville, Beulah Bondi, Zasu Pitts, Billie Burke and Hedda Hopper. Musical performances are provided by Nat King Cole and the King Cole Trio, along with Spike Jones and his City Slickers.

A Depression-downtrodden waif uses her brains instead of her body to rise from tyro con artist to crime boss.

Two destitute New Yorkers meet cute in Central Park and then separate and independently get tangled up with some gangsters only to be reunited again in the end.

Two big city lawyers are handed an important case but then find it requires them to deal with the oddball and very shrewd characters in a small town.

A young law graduate joins his older brother's legal practice, only to discover the firm's clients are mostly mobsters.

Madge Winton, a beautiful secretary, makes herself look homely in order to avoid advances by lecherous bosses. When her new employer, writer Freddy Matthews, accidentally sees her without her disguise, she has to pretend to be her roommate Sadie.

Former bootlegger Remy Marco has a slight problem with foreclosing bankers, a prospective son-in-law, and four hard-to-explain corpses.

When retired racket boss John Sarto tries to reclaim his place and former friends try to kill him, he finds solace in a monastery and reinvents himself as a pious monk.

When bookseller Buzz cons Diana into thinking that his friend Stanley knows all there is to know about Africa, they are abducted and ordered to lead Diana and her henchmen to an African tribe in search of a fortune in jewels.